Contraceptive use and increased risk of thrombosis?

It’s interesting to note that contraceptives can increase risk of thrombosis. A report in 1980 showed that two women who died of myocardial infarction did not smoke or have hyperlipidemia, hypertension or atherosclerosis; the only connection was an oral contraceptive (1). I’d like to learn more about why this would happen.

1. Loire R, Touboul P, Gressard A, Rondepierre D, Tabib A. [Oral contraceptive and coronary thrombosis. Two clinicopathological cases]. Arch Mal Coeur Vaiss 1980;73:432-7.


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