Evolving Health

Monthly Archives: August 2009

Humans contain about 2-4g iron of which most is in hemoglobin and to a lesser extent myoglobin. Iron from diet is found in heme (animal foods) and nonheme (plant foods) forms. The heme iron needs to be hydrolyzed where as the nonheme is enzymatically freed. Heme iron is absorbed intact accross the brushborder of the enterocyte whereas nonheme iron is released as ferric in the stomach, which may be reduced to ferrous…. Read More

A mineral supplement I’ve taken in the past includes 10mg zinc and 1mg of copper. Thus, the amount of zinc is not at the “higher than 50mg” level that can cause a copper deficiency because of interference with bioavailability (1). This is exactly the 10:1 ratio as suggested to avoid any copper deficiency (2). Someone did his/her homework. 1. http://lpi.oregonstate.edu/infocenter/minerals/zinc/2. http://www.pccnaturalmarkets.com/health/2934002/

1 chicken drumstick, broilers or fryers, meat and skin, cooked, roasted = 2.98mg3 Eggs, whole, cooked, scrambled = 1.83mg1 burrito, bean and cheese, microwaved = 1.33mg1 cup milk, whole, 3.25% milkfat = .98mg1 fish fillet, trout, rainbow, farmed = .32mg Data found at: http://www.nal.usda.gov/fnic/foodcomp/

Purpose of study: Zinc and copper are lost in significant amounts in acute diarrhea and zinc has been suggested as a therapy for its possible facilitation of water and electrolyte transport across intestinal mucosa to prevent villous atrophy and modulate immune response. This study evaluated whether or not zinc and copper supplementation had any beneficial effect on acute watery or bloody diarrhea when given with standard treatment. Type of study: Randomized, double-blinded… Read More

Armour thyroid is the “natural” therapy from dessicated porcine thyroid gland while Synthroid is produced synthetically as levothyroxine. Armour thyroid contains both T3 and T4 while Synthroid only contains T4. There is debate on whether or not use of both or one is better. Synthroid came into use because it was standardized unlike the natural kind, which varied a lot from batch to batch. But it turns out that patients often don’t… Read More

To regulate basal metabolic rate, the thyroid gland synthesizes hormones thyroxine, or triiodo-L-thyronine (T4), and the more active triiodo-L-tyronine (T3) (1).When secreted into the bloodstream, they associate with transport proteins (thyroxine-binding globulin, albumin, and transthyretin), which circulate the hormones (2). There is nearly 50 times T4 than there is T3, but T3 is more potent. T4 and T3 bind to nuclear receptors that affect gene expression. Increased mRNA and protein synthesis appear… Read More

As iron deficiency develops gradually without anemia, symptoms can appear that can include pallor and problems of behavior, cognition, learning and attention span. These can particularly manifest themselves in children. Adults may witness problems related to work performance and productivity. The effects may be related to impairment of the neurotransmitter gamma-aminobutyric acid (GABA) used to inhibit dopamine production in the brain and/or immune system impairment leading to more susceptibility to infection and… Read More

Hemochromatosis is a genetic disorder caused by one of several mutations related to double-than-normal iron absorption, which increases susceptibility to iron overload (1). Although the disorder affects about one in 200 in the U.S., it’s still largely unrecognized and can lead to deposits in organs—such as the liver—leading to organ damage and failure if not treated early enough (2-4). Because the disorder is most prevalent in males of Northern European ancestry, particularly… Read More

Korsakoff’s syndrome, or Wernicke encephalopathy, is a serious neurological disorder occurring under conditions of thiamine deficiency. It’s usually caused by long-term abuse of alcohol, which breaks down thiamine in the body. It is characterized at autopsy by lesions in the brain stem. Thiamine is necessary for proper glucose metabolism in the brain (1). As a B vitamin it acts as a cofactor for enzymes in the Krebs cycle including pyruvate dehydrogenase. Brain… Read More

Type 2 diabetes mellitus is considered a major risk factor in cardiovascular disease (CVD) in both men and women, but CVD pathogenesis biochemistry can differ between the sexes. Both sexes are affected by insulin resistance, which generally precedes the diabetes, and accompanying metabolic syndrome factors dyslipidemia and hypertension (1). The insulin resistance leads to elevated insulin levels, which stimulates sodium reabsorption. The sodium levels can induce prolonged hypertension. The hypertension leads to… Read More