When do you need arginine?

Arginine is used for synthesis of protein, agmatine, polyamines and creatine [1]. Because kidneys synthesize arginine usually in sufficient amounts in the urea cycle(releasing 2-4g daily), it’s normally not necessary to attain it from the diet [1p196;229]. At times, however, arginine can become conditionally essential [1p229]. Such times would include protein malnutrition, excessive ammonia production,Continue reading “When do you need arginine?”

How is urea regulated?

Urea cycle regulation is dependent on dietary factors and hormone concentrations (1). A feed-forward regulation exists in that available ammonia causes more urea to be created (1). This can also mean that higher protein can also act as a feed-forward regulation since it increases urea enzyme levels (1-2). Ammonia can come from diet, from deamination,Continue reading “How is urea regulated?”

“Goods” and “bads” of extra protein in sports

While Dietary Reference Intakes for protein are 0.8g protein per kg for adults, data suggest athletes may need more depending on their sport, particularly strength-training athletes (1). Research also indicates that even non-athletes who weight train may benefit from the added protein (2). Endurance exercise sports such as cycling and running increase protein turnover, includingContinue reading ““Goods” and “bads” of extra protein in sports”

Spoonful of any kind of sugar makes the protein go down after exercise

It’s clear that carbohydrates with protein affects insulin, thereby inducing glycogen synthesis. However, I was left thinking, “But what kind of carbohydrate is best?” And I found a study that suited my curiosity. One published in 2007 in J Int Soc Sports Nutr showed that 40 subjects who weight trained taking 40g of whey proteinContinue reading “Spoonful of any kind of sugar makes the protein go down after exercise”

Can arginine make you look like Arnold?

Arginine is a precursor for nitric oxide, which relaxes vascular smooth muscle leading to improved blood flow and, thus, the flow of nutrients to muscles (1;2). Oral arginine appears to also stimulate growth hormone release, especially when taken with exercise (3). Supplementation with arginine didn’t increase body mass significantly in a study in 2008; although,Continue reading “Can arginine make you look like Arnold?”

Will glutamine give you big guns?

You might think so. In theory, glutamine supplementation appears to make sense. Supplementation increases plasma glutamine in the plasma (1), which is thought to support the immune system (2;3) because the immune system uses glutamine for energy production (4). Plus, because exercise causes muscles to increase use of glutamine, stores are depleted (4). However, accordingContinue reading “Will glutamine give you big guns?”

Trans fats increase diabetes risk more than saturated fats

Saturated fats including trans fat can lead to a increased risk of cardiovascular disease mainly by raising cholesterol and causing a poor LDL:HDL ratio (1). Trans fat is thought to be more atherogenic because it has also been found to lower HDL cholesterol in studies (1-3). But what about diabetes risk? In 2006 a reviewContinue reading “Trans fats increase diabetes risk more than saturated fats”

Do eggs raise cholesterol?

The presence of ovomucin, a natural trypsin inhibitor in eggs, can help block some of egg cholesterol absorption and bile acid reabsorption through enterohepatic circulation (1). Despite ovomucin, however, there does appear to be enough dietary cholesterol in eggs absorbed that can potentially cause increased cholesterol levels (2;3). Reference List1. Nagaoka S, Masaoka M, ZhangContinue reading “Do eggs raise cholesterol?”

Good and bad reasons to cook eggs

Raw egg white contains avidin. As dietary protein is digested, the presence of avidin can bind to biotin tightly preventing its absorption into the body (1). Because biotin is used as a prosthetic group in acetyl CoA carboxylase, a biotin deficiency can then inhibit the carboxylation reaction catalyzed by acetyl CoA carboxylase that converts malonylContinue reading “Good and bad reasons to cook eggs”

Lovastatin versus cholestyramine for familial hypercholesterolemia

Along with the recommendation of exercise and a healthy diet (including a bit of red wine daily), both lovastatin and cholestyramine can be used in the treatment of familial hypercholesterolemia (1;2). While lovastatin works as a HMG CoA reductase inhibitor to reduce cholesterol synthesis in the liver, cholestyramine acts as a bile acid-binding resin thatContinue reading “Lovastatin versus cholestyramine for familial hypercholesterolemia”