Chromium nicotinate, but not picolinate may improve body composition

Advertisements that suggest chromium picolinate may help consumers lose fat or gain muscle mass are largely overstated. A double-blind, randomized, placebo-controlled 12-week trial in 2001 found that chromium picolinate offered moderately obese women participating in an exercise program no significant changes to body composition, resting metabolic rate, plasma glucose, serum insulin, plasma glucagon, serum C-peptideContinue reading “Chromium nicotinate, but not picolinate may improve body composition”

Selenium and Prostate Cancer

Prostate cancer has been associated with low serum selenium concentration. To investigate the mechanisms by which selenium affects gene expression prostate tissue, researchers set out to measure activity of glutathione peroxidase in men with relatively high serum selenium concentration (1). The researchers measured serum selenium concentration in 98 men using atomic absorption spectrometry. Afterward, 12Continue reading “Selenium and Prostate Cancer”

Zinc and copper not effective for acute diarrhea

Purpose of study: Zinc and copper are lost in significant amounts in acute diarrhea and zinc has been suggested as a therapy for its possible facilitation of water and electrolyte transport across intestinal mucosa to prevent villous atrophy and modulate immune response. This study evaluated whether or not zinc and copper supplementation had any beneficialContinue reading “Zinc and copper not effective for acute diarrhea”

Iron Deficiency Symptoms

As iron deficiency develops gradually without anemia, symptoms can appear that can include pallor and problems of behavior, cognition, learning and attention span. These can particularly manifest themselves in children. Adults may witness problems related to work performance and productivity. The effects may be related to impairment of the neurotransmitter gamma-aminobutyric acid (GABA) used toContinue reading “Iron Deficiency Symptoms”

Hemochromatosis a Neolithic adaptation?

Hemochromatosis is a genetic disorder caused by one of several mutations related to double-than-normal iron absorption, which increases susceptibility to iron overload (1). Although the disorder affects about one in 200 in the U.S., it’s still largely unrecognized and can lead to deposits in organs—such as the liver—leading to organ damage and failure if notContinue reading “Hemochromatosis a Neolithic adaptation?”

Potassium Guards Against Sodium-induced Bone Loss

Reference: Sellmeyer DE, Schloetter M, Sebastian A. Potassium citrate prevents increased urine calcium excretion and bone resorption induced by a high sodium chloride diet. J Clin Endocrinol Metab 2002;87:2008-12. Available at: Purpose of study: To study effects of dietary potassium citrate added to diets high in sodium, as commonly found in industrialized nations, inContinue reading “Potassium Guards Against Sodium-induced Bone Loss”

Why Gatorade May Not Rehydrate You Any Faster Than Water

Research Summary Critique Reference: Jeukendrup AE, Currell K, Clarke J, Cole J, Blannin AK. Effect of beverage glucose and sodium content on fluid delivery. Nutr Metab (Lond) 2009;6:9. Available at: Purpose of study: The objective of many oral rehydration drinks is rapid fluid delivery to correct fluid balance in sports. This study investigated carbohydrateContinue reading “Why Gatorade May Not Rehydrate You Any Faster Than Water”